Performance Analysis in Vitro Method of Antimicrobial Activity in Different Commercial Antibiotics

Authors

  • Allabaksha Mahboob Shaikh M. C. E. society's Allana Collage of pharmacy. 2390-B, Hidayatullah Road, Azam Campus, Pune-411001.
  • P.Dharani Prasad Department of Pharmacology, MB School of Pharmaceutical sciences MB University (Erstwhile Sree Vidyaniketan College of Pharmacy) Tirupati Andhra Pradesh 517102.
  • Neha RKSD College of pharmacy, Kaithal (Haryana) 136027.
  • Jiwan Premchand Lavande Fabtech College of Pharmacy, Sangola.
  • Azad Nabilal Dhage Ashokrao Mane Institute of Pharmaceutical Sciences and Research, Save. Tal- Shahuwadi, Dist- Kolhapur. 416213.
  • Megha Salve Shivajirao Pawar College of Pharmacy At post pachegao Tal newasa District Ahmednagar 431005. 7SMES mahavir institute of pharmacy nashik
  • kajal uttam khurdal SMES mahavir institute of pharmacy nashik
  • Sayyed Mateen Oriental College of Pharmacy, Sanpada, Navi-Mumbai. 400705

DOI:

https://doi.org/10.53555/jaz.v44iS3.815

Keywords:

vitro method, antimicrobial activity, commercial antibiotics.

Abstract

This study was motivated by the fact that certain food poisonings and harmful microorganisms in ethanol and water determine roselle (Hibiscus sabdariffa), rosemary (Rosmarinus officinalis), clove (Syzygium aromaticum), and thyme (Thymus vulgaris). is to exhibit the capacity to eliminate Least inhibitory focuses (MICs) of different plant extricates against Gram-positive microorganisms (Bacillus cereus, Staphylococcus aureus), Gram-negative microscopic organisms (Escherichia coli, Enteritidis, Vibrio parahaemolyticus, Pseudomonas aeruginosa) and parasites (Candida albicans) and antibacterial impacts were explored. It is dissolved and measured using the agar well dispersion technique. The concentrate showed antimicrobial efficacy against the microorganisms and yeast used in the tests. Both pHint reduction and cell layer hyperpolarization indicated that the plant extract had a profound effect on the membranes of Gram-positive and Gram-negative microorganisms. Overall, plant extracts have significant potential as unique regular food additives due to their antibacterial properties.

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Published

2023-10-12

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