Ameliorating Effect Of Myrica Esculenta In Alzheimer's Mice Model
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Abstract
Alzheimer disease (AD) is a neurodegenerative ailment that is typified by psychological and behavioral impairment that significantly inhibits a person's capacity to engage in day-to-day living activities. Around one in ten persons who are over the age of 65 and around one third of those who are over the age of 85 are affected by it The practice of phytotherapy, which involves the consumption of herbal remedies, has the potential to serve as a foundational element upon which therapeutic approaches might
be simplified. Therefore, the current work was conducted to investigate the anti-alzheimeric effects of plant extract from Myrica esculenta. The Morris water maze (MWM), elevated plus maze (EPM), and passive avoidance tests (PAT), Marble burying test were used to examine the impact of Myrica esculenta ethanol extracts on scopolamine-induced memory impairment in mice. Ethanolic extract of Myrica esculenta obtained from ethanol. In add These extracts, when given orally, were shown to enhance learning and memory in mice as measured by the Morris Water Maze, the Elevated Plus-Maze, and Marble burying test.
This research suggests that Myrica esculenta might be used as effective therapeutic compounds in the fight against neurodegeneration. Potential therapeutic benefits of the plants may be enhanced by their unique pharmacological activity.
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